Peyronie’s Disease (and various forms of penile deformities)

Peyronie’s disease is not an uncommon penile condition affecting men and it is estimated that 1 in 9 Australian men has this condition (Professor Chung published the first national study on Peyronie’s disease in Australia).

 

It refers to a constellation of symptoms namely penile pain, curvature or deformity, length loss, fibrous plaque and ultimately sexual dysfunction. Peyronie’s disease is thought to occur following certain trauma to the erect penis and less than a third of men report complete resolution of their symptoms. While Peyronie’s disease is not a life-threatening condition, it can lead to significant impairment in sexual functioning and psychological distress.

 

 

If you complain of painful erection and penile deformity (penile curvature or length loss), you should seek medical attention because there are various effective treatment options available for Peyronie’s disease. Sometimes you may be required to undergo further tests such as penile colour Duplex study to evaluate the smooth muscle and underlying vascular supply of your penis.

Professor Chung has published extensively on penile reconstructive surgery (see below) and is considered the leading surgeon expert in Australia and worldwide. He is the only surgeon in Australia invited to serve on Peyronie’s disease and penile reconstructive committee at the International Consultation on Sexual Medicine, the peak authority body for the International Society of Sexual Medicine. He is the lead author on several major Peyronie’s disease clinical guidelines. He has mentored many surgeons over the years including being invited as surgeon expert and organised numerous surgical workshops around the world. He is often asked to see complex and salvage cases by other surgeons to restore penile size and shape in difficult patients.

Treatment options for Peyronie’s disease

The treatment options for Peyronie’s disease vary depending on the clinical findings and severity of the Peyronie’s disease. Your options include oral medications, penile traction device, injectable agents to dissolve the penile plaque, or penile surgery. In general, if your penile curvature and plaque have been stable for more than 6 months, you are likely to require reconstructive surgery such as penile plication or graft. Penile prosthesis implant surgery is advocated if you have coexisting erectile dysfunction.

Some of the key articles published by Professor Chung on Peyronie’s disease

  • Chung E, Bettocchi C, Egydio P, Love C, Osmonov D, Park S et al. The International Penile Prosthesis Implant Consensus Forum: Clinical recommendations and surgical principles on the inflatable 3-piece penile prosthesis implant. Nat Rev Urol. 2022;19(9):534-546
  • Chung E, Yafi FA. Pharmacotherapy in Peyronie’s disease: a state-of-the-art review on established contemporary and emerging drugs Expert Opin Pharmacother. 2022;1-8
  • Chung E. Editorial commentary: Is social media a reliable source of information on Peyronie’s disease treatment? Int J Impot Res. 2022;34(3):321-322
  • Chung E, Gillman M, Tuckey J, La Bianca S, Love C. A clinical pathway for the management of Peyronie’s disease: integrating clinical guidelines from the International Society of Sexual Medicine, American Urological Association, and European Urological Association. BJU Int. 2020;126 (Suppl 1):12-17
  • Chung E. Penile prosthesis implant in the special populations: diabetics, neurogenic conditions, fibrotic cases, concurrent urinary incontinence, and salvage implants. Asian J Androl. 2020;22(1):39-44
  • Chung E, Gillman M, Rushton D, Love C, Katz D. Prevalence of penile curvature: a population-based cross-sectional study in metropolitan and rural cities in Australia. BJU Int. 2018;122(Suppl 5):42-49
  • Chung E, Wang R, Ralph D, Levine L, Brock G. A worldwide survey on Peyronie’s disease surgical practice patterns among surgeons. J Sex Med. 2018;15(4):568-75
  • Chung E. Penile reconstructive surgery in Peyronie’s disease: Challenges in restoring normal penis size, shape and function. World J Mens Health. 2018; 36:e10-17
  • Chung E, Ralph D, Kadioglu A, Garaffa G, Shamsodini A, Bivalacqua T, Glina S, Hakim L, Sadeghi-Nejad H and Broderick G. Evidence-based management guidelines on Peyronie’s Disease. J Sex Med. 2016;13(6):905-23
  • Chung E. Pro: does shockwave therapy have a place in the treatment of Peyronie’s disease? Transl Androl Urol. 2016;5(3):366-70
  • Chung E. Diagnosis and management of Peyronie’s disease: an evidence-based review. Trends in Urology Men’s Health. 2015;6(1):18-22
  • Chung E, De Young L, Solomon M and Brock GB. Peyronie’s disease and mechanotransduction: An in vitro analysis of the cellular changes to Peyronie’s disease in a cell-culture strain system. J Sex Med 2013;10(5):1259-67
  • Chung E, Solomon M, DeYoung L and Brock GB. Comparison between AMS 700 CX and Coloplast Titan penile prosthesis for Peyronie’s disease treatment and remodelling: Clinical outcomes and patient satisfaction. J Sex Med 2013;10(5):1259-67
  • Chung E and Brock GB. Penile traction therapy and Peyronie’s disease: A state of art review of the current literature. Ther Adv Urol. 2013;5(1):59-65
  • Chung E, Yan H, De Young L and Brock GB. Penile Doppler sonographic and clinical characteristics in Peyronie’s disease and/or erectile dysfunction: An analysis of 1500 men with male sexual dysfunction. BJU Int 2012;110(8):1201-5
  • Chung E and Brock GB. Duplex sonographic study of impotent men with Peyronie’s disease: is veno-occlusion the cause? J Sex Med 2011;8(12):3446-51
  • Chung E, Cledinning E, Lessard L and Brock GB. Five Year Follow-Up of Peyronie’s Graft Surgery: Outcomes and Patient Satisfaction. J Sex Med. 2011;8(2):594-600
  • Chung E, DeYoung and Brock GB. Rat as an animal model for Peyronie’s disease research: A review of current methods and the peer-reviewed literature. Int J Impot Res. 2011;23(6):235-41